Mr. Ron Nagar reports

TEMPRAMED RECEIVES FIRST COMMERCIAL ORDER FROM ISRAEL DISTRIBUTOR AND COMPLETES INITIAL SHIPMENT ENABLING ENTRY INTO NATIONAL PHARMACY NETWORK

Tempramed Technologies Ltd. has received its first commercial order in Israel and has delivered an initial shipment to the warehouse of Guri AAO, a leading Israeli medical distribution company.

Guri is among the top-five distributors in Israel's retail sector and brings more than 50 years of industry leadership. The company exclusively distributes a wide range of internationally recognized brands, including GSK/Haleon oral care products and Cargill's Truvia natural sweeteners, and maintains deep, long-standing relationships with 2,500 of Israel's largest supermarkets, pharmacy chains, HMOs and independent pharmacies.

This milestone marks the commencement of Tempramed's commercial activities within the Israeli retail bricks and mortar pharmacy channel, representing a significant expansion of the company's go-to-market strategy. In addition to its established direct-to-consumer activities, the collaboration with Guri adds a dedicated business-to-business layer, enabling broader access to Tempramed's temperature protection solutions through pharmacy networks in Israel.

The collaboration in Israel builds on Tempramed's growing portfolio of commercial partnerships across Europe, Asia and other international markets, reinforcing the company's global expansion strategy and diversified channel approach.

Israel represents a highly advanced health care market with strong adoption of injectable therapies, including insulin, GLP-1 receptor agonists, biologics and emergency medications. As the use of temperature-sensitive medications continues to grow, ensuring protection from heat and cold exposure throughout daily life is increasingly critical to maintaining medication effectiveness and patient safety and wellness.

The initial shipment delivered to Guri's warehouse establishes operational readiness for retail pharmacy distribution and lays the foundation for expanded availability across pharmacies and health care channels nationwide. By leveraging Guri's established infrastructure and relationships within the Israeli health care ecosystem, Tempramed aims to increase market penetration and strengthen its presence nationally.

"This first commercial order and delivery to Guri marks an important operational and commercial milestone for Tempramed," said Ron Nagar, chief executive officer of Tempramed. "We are making the leap from being a purely on-line retailer to physical stores. We have now successfully entered our target segment: B2B commerce. This was achieved not only through the outstanding user experience of Vivi technology, but also thanks to our excellent sales team, which secured multiple contracts with global distributors in a very short time. We have ambitious plans for 2026 and are well on our way to realizing our own vision, as well as that of our shareholders."

About Tempramed Technologies Ltd.

Tempramed is a global leader in innovative, temperature-controlled medication storage solutions. Founded with the mission to safeguard the effectiveness of life-saving medications, Tempramed develops patented, Food and Drug Administration-registered, space-grade thermal insulation devices that work 24-seven without batteries or external power. With a proven product line including Vivi Cap and Vivi Epi, and a smart technology platform on the horizon, Tempramed enables patients and health care providers to confidently manage temperature-sensitive medications anywhere, any time. With operations in North America, Europe and Asia, Tempramed is advancing the future of medication protection and adherence.

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