The Globe and Mail reports in its Thursday edition that shares in Spanish pharmaceutical company Grifols SA rose on Wednesday after Brookfield Asset Management said it was talking with shareholders. A Reuters dispatch to The Globe says that followed a report on website El Confidencial that Brookfield was considering a new takeover attempt. In a filing to the Madrid stock market regulator, Brookfield, however, said it was not in talks with the company's board over a potential takeover bid. In its stock market filing, Brookfield said it maintained "a general dialogue with Grifols' reference shareholders" without being more specific. El Confidencial had said that Brookfield was in talks with the Grifols family, the company's largest shareholder, and was considering making an offer valuing the company at seven billion euros ($10.88-billion). A non-binding offer that valued Grifols at 6.45 billion euros ($10.02-billion) was withdrawn by Brookfield in November after Grifols rejected it as too low and recommended shareholders keep their shares. Despite the Brookfield denial of a takeover bid, El Confidencial's citing of an offer significantly higher than the value offered in November fuelled speculation on Grifols's shares.