Mr. Rav Mlait reports

CANNABIX TECHNOLOGIES EVALUATING EXPANSION INTO BREATH-BASED HEALTH AND BIOMARKER MARKET WITH PROPRIETARY BCU "VOC" PLATFORM

Cannabix Technologies Inc. is evaluating its breath collection unit (BCU) technology, for strategic expansion into the rapidly advancing breath biomarker research and diagnostics sector. The company has developed a version of its BCU that can be target volatile organic compound (VOC) in breath samples applicable for health, biomarker and environmental testing markets.

This proposed BCU VOC device is designed as a portable, standardized breath collection platform that builds directly on the company's existing hardware infrastructure, adapting it to capture samples onto industry-standard thermal desorption (TD) tubes. Because the technology leverages Cannabix's pre-existing drugs of abuse BCU platform, Cannabix can offer this solution to the medical research market with minimal additional research and development (R&D) expenditure.

Addressing a critical industry gap

Breath-based biomarker research is advancing quickly as global institutions seek non-invasive methods to detect diseases such as cancers, metabolic disorders and infectious illnesses. However, the market for standardized, portable breath collectors that utilize industry-standard TD tubes is limited.

Only a limited number of companies have developed dedicated human breath collection devices specifically designed to standardize preanalytical sampling variables for downstream mass spectrometry analysis. Today, the market remains fragmented between low-technology collection methods, such as breath bags and industrial pump-based systems, which can suffer from variability and workflow limitations, and closed, vertically integrated platforms that require users to operate within proprietary data and analytical ecosystems.

The company is evaluating this opportunity to utilize the VOC platform as an independent breath collection infrastructure provider rather than a diagnostics, data analytics or disease interpretation company. This hardware-focused approach may position Cannabix as a neutral technology partner capable of supporting a broad range of end users, including cancer research centres, pharmaceutical and biotechnology companies, hospitals and health care systems, academic researchers, and global contract research organizations (CROs). By remaining platform-agnostic, Cannabix has the potential to enable breath collection workflows across multiple applications, studies and analytical platforms without competing with its customers in the downstream analysis or diagnostic market.

The breath analysis and biomarker market is seeing increased capital commitment from public and philanthropic entities focused on clinical standardization. Major organizations -- including the Bill & Melinda Gates Foundation, and the Advanced Research Projects Agency for Health (ARPA-H) -- have financed large initiatives to establish uniform protocols for collecting and analyzing VOCs in human breath.

Advantages of the BCU VOC platform

Due to its portable, handheld, rugged and user-friendly design, the BCU VOC platform has the potential to enable the standardized collection of breath samples across multiple locations, including non-clinical settings and large population groups. This capability may support decentralized and multicentre clinical studies by facilitating consistent breath sample collection outside traditional laboratory environments. The platform's standardized collection approach may also improve data comparability across sites while reducing logistical complexities associated with conventional breath sampling methods.

The device has key features to address preanalytical variability challenges by regulating and measuring breath flow and volume. In addition, the BCU VOC holds the multifunctional capability to be utilized as an ambient air collector for environmental sampling, providing a dual-market application for medical, occupational and research needs.

Furthermore, there is an opportunity to service laboratories and CROs that seek a hardware supplier that does not compete with them on data analysis or proprietary diagnostic algorithms. Cannabix would offer an objective, hardware-only alternative, allowing labs to retain complete control over their own analytical mass-spectrometry and biomarker discovery pipelines. By operating strictly as a neutral hardware and consumables vendor under research use terms, the company may be able to fast-track its entrance into labs while completely bypassing the lengthy, multiyear clinical trial pathways required for diagnostic medical devices.

About Cannabix Technologies Inc.

Cannabix Technologies is a leading developer of breath-based technologies designed to enhance public safety and reduce impairment-related risks in workplaces, law enforcement, and a range of different settings. The marijuana breath test (MBT) targets delta-9 THC-the primary psychoactive compound in cannabis-in breath, providing a practical solution for identifying recent marijuana use.

The BreathLogix, unmanned alcohol screening solution supports organizations in pro-actively monitoring alcohol impairment, strengthening safety protocols and promoting responsible behaviour. By delivering innovative, non-invasive screening tools, Cannabix aims to help reduce accidents, improve decision-making and protect organizations, individuals, and the public at large.

We seek Safe Harbor.