Mr. Albert Friesen reports

MEDICURE REPORTS FINANCIAL RESULTS FOR QUARTER ENDED MARCH 31, 2024 AND ANNUAL GENERAL MEETING DIRECTOR ELECTION RESULTS

Medicure Inc. has released its results from operations for the quarter ended March 31, 2024.

The Company is also pleased to announce the voting results for the election of directors at its annual meeting of shareholders held earlier today (the "Meeting"). Each of the six nominees listed in Company's management information circular dated April 12, 2024, namely Dr. Albert Friesen, Dr. Arnold Naimark, James Kinley, Kimberly Kramchynsky, Brent Fawkes and Peter Quick, was elected as a director of Medicure to hold office until the next annual meeting of shareholders or until their successor is duly elected. Each director received votes for totalling greater than 99%.

Kimberly Kramchynsky, more commonly known as Kim Kline, is the only newly appointed director. Ms. Kline is currently on the board of BioTalent Canada and the advisory board of RRC Polytech Life Sciences. She is also the past President of the Bioscience Association of Manitoba, a position she held until early 2024, and a former member of the University of Manitoba Faculty of Science Dean's advisory board.

"We are pleased to welcome Kim to our Board" said Albert Friesen, Chair of Medicure's Board of Directors. "She has a breadth of experience and relationships in the bioscience industry, and brings strong leadership and strategic planning skills to the position".

Quarter Ended March 31, 2024 Highlights:

Recorded total net revenue of $5.7 million during the quarter ended March 31, 2024 compared to $5.6 million for the quarter ended March 31, 2023 and;

Recorded total net revenue from the sale of AGGRASTAT(TM) of $2.3 million during the quarter ended March 31, 2024 compared to $2.7 million for the quarter ended March 31, 2023 and;

Recorded total net revenue from the Marley Drug business of $2.7 million ($770,000 from sales of ZYPITAMAG(TM), and $1.9 million from other pharmacy revenue) during the quarter ended March 31, 2024 compared to $2.3 million ($580,000 from sales of ZYPITAMAG and $1.7 million from other pharmacy revenue) for the quarter ended March 31, 2023 and;

Recorded total net revenue from the sale of ZYPITAMAG of $777,000 during the quarter ended March 31, 2024 compared to $640,000 through insured business for the quarter ended March 31, 2023 and;

Adjusted earnings before interest, taxes, depreciation and amortization (EBITDA1) for the quarter ended March 31, 2024 was $359,000 compared to adjusted EBITDA of $916,000 for the quarter ended March 31, 2023 and;

Net income for the quarter ended March 31, 2024 was $51,000 or $0.00 per share compared to net income of $290,000 or $0.03 per share for the quarter ended March 31, 2023.

Financial Results

The modest decrease in AGGRASTAT revenues when compared to the same period in the previous year, as described above, is the result of an increase in pricing competition from generic tirofiban hydrochloride in 2024 when compared to 2023.

The Marley Drug business contributed $2.7 million of revenue for the quarter ended March 31, 2024 compared to $2.3 million for the quarter ended March 31, 2023. Marley Drug is a US pharmacy licensed to ship medications to all 50 states, Washington D.C. and Puerto Rico. The increase in revenue is a result of increased sales through marketing, fulfillment partnerships, its e-commerce platform, and increased sales of ZYPITAMAG.

ZYPITAMAG through insured channels contributed $777,000 of revenue for the quarter ended March 31, 2024 compared to $640,000 through insured channels for the quarter ended March 31, 2023. The increase in revenues in 2024 is due to an increased volume of sales to drug wholesalers, in response to stronger demand for ZYPITAMAG through insured channels.

Adjusted EBITDA for the quarter ended March 31, 2024 was $359,000 compared to $916,000 for the quarter ended March 31, 2023. Decreased adjusted EBITDA for the quarter ended March 31, 2024 resulted from lower AGGRASTAT revenue, higher general and administrative expenses and higher research and development expenses.

Net income for the quarter ended March 31, 2024 was $51,000 or $0.00 per share compared to net income of $290,000 or $0.03 per share for the quarter ended March 31, 2023. The main factors contributing to the decrease in net income recorded for the quarter ended March 31, 2024 were lower AGGRASTAT revenue, higher general and administrative expenses and higher research and development expenses, offset by insurance proceeds received by the Company for AGGRASTAT inventory which had previously been damaged in import.

At March 31, 2024, the Company had unrestricted cash totaling $6.1 million, a decrease from $6.4 million of unrestricted cash held as of December 31, 2023. Cash flows used in operating activities for the quarter ended March 31, 2024 was $132,000 compared to cash from operating activities of $173,000 for the period ended March 31, 2023.

All amounts referenced herein are in Canadian dollars unless otherwise noted.

The full financial statements are available at www.sedar.com and on the Company's website at www.medicure.com.

NotesThe Company defines EBITDA as "earnings before interest, taxes, depreciation and amortization" and Adjusted EBITDA as "EBITDA adjusted for non cash and non-recurring items". The terms "EBITDA" and "Adjusted EBITDA", as it relates to the three month period ended March 31, 2024 and 2023 results prepared using IFRS, do not have any standardized meaning according to IFRS.

Conference Call Info:

Topic: Medicure's Q1 2024 Results

Call date: Wednesday, May 29, 2024

Time: 7:30 AM Central Time (8:30 AM Eastern Time)

Toll Free: 1 (888) 506-0062

International: 1 (973) 528-0011

Participant Access Code: 780348

Webcast: This conference call will be webcast live over the internet at the following link: https://www.webcaster4.com/Webcast/Page/2965/50707

You may request international country-specific access information by e-mailing the Company in advance. Management will accept and answer questions related to the financial results and operations during the question-and-answer period at the end of the conference call. A recording of the call will be available following the event at the Company's website.

About Medicure Inc.Medicure is a company focused on the development and commercialization of pharmaceuticals and healthcare products for patients and prescribers in the United States market. The present focus of the Company is the marketing and distribution of AGGRASTAT(TM) (tirofiban hydrochloride) injection and ZYPITAMAG(TM) (pitavastatin) tablets in the United States, where they are sold through the Company's U.S. subsidiary, Medicure Pharma Inc. Medicure also operates Marley Drug Inc. ("Marley Drug"), a pharmacy subsidiary servicing all 50 states, Washington D.C. and Puerto Rico. Marley Drug(TM) is committed to improving access to medications for all Americans together with exceptional customer service and free home delivery. For more information visit www.marleydrug.com. For more information about Medicure please visit www.medicure.com. For additional information about AGGRASTAT(TM), please visit www.aggrastat.com or refer to the full Prescribing Information. For additional information about ZYPITAMAG(TM), please visit www.zypitamag.com or refer to the full Prescribing Information.

We seek Safe Harbor.