Mr. Ron Nagar reports

TEMPRAMED SIGNS LETTER OF INTENT WITH CPO CYPRUS FOR EXCLUSIVE DISTRIBUTION OF Vivi PRODUCTS IN CYPRUS

Tempramed Technologies Ltd. has signed a non-binding letter of intent (LOI) dated July 31, 2026, with Cyprus Pharmaceutical Organization Ltd. (CPO Cyprus) regarding the proposed exclusive distribution of Vivi Cap and Vivi Epi in Cyprus.

Highlights:

• LOI with CPO Cyprus includes exclusive distribution of Vivi Cap and Vivi Epi throughout Cyprus, subject to a definitive agreement;
• Proposed exclusivity is conditional on minimum annual purchase obligations, with combined purchases required to increase by at least 20 per cent year over year to maintain exclusivity;
• Transfer pricing and the first-year minimum combined unit commitment will be negotiated and established in the definitive distribution agreement;
• CPO Cyprus brings nearly a century of local market experience and established distribution capabilities spanning pharmaceutical products, medical instruments and hospital equipment.

Under the LOI, Tempramed proposes to appoint CPO Cyprus as the exclusive distributor of Vivi Cap and Vivi Epi in Cyprus, subject to the execution of a definitive distribution agreement and CPO Cyprus's compliance with minimum purchase obligations. The specific transfer prices and first-year minimum combined unit commitment have not yet been finalized and are to be established in the definitive agreement.

To maintain the proposed exclusivity, CPO Cyprus would be required to increase its total annual combined purchases of Vivi Cap and Vivi Epi by no less than 20 per cent year over year. The LOI provides a 90-day period from July 31, 2026, for the parties to negotiate and conclude a definitive agreement, unless extended by mutual agreement.

CPO Cyprus was founded in Nicosia in 1928 and, according to CPO Group, has grown to rank among the 20 largest trading firms in Cyprus. The company is an importer, distributor and exclusive agent across the health, beauty, personal care and food sectors, with products ranging from pharmaceuticals to specialized medical instruments and hospital equipment.

Tempramed believes CPO Cyprus's health care market experience, established local relationships and distribution capabilities make it a strong prospective partner for the company's entry into Cyprus.

The proposed relationship supports Tempramed's strategy of expanding through experienced local partners that can navigate country-specific health care channels and build sustained product adoption. If a definitive agreement is completed, Cyprus would become an additional European market for two of Tempramed's commercial medication-protection products.

"CPO Cyprus is exactly the kind of established, market-facing partner we want as we expand Tempramed's global commercial footprint," said Ron Nagar, founder and chief executive officer of Tempramed. "With roots in Cyprus dating back nearly a century and broad experience across pharmaceutical and medical product distribution, CPO Cyprus offers a strong prospective platform for introducing Vivi Cap and Vivi Epi nationwide. The proposed annual purchase growth requirement reflects our intention to build this relationship for scale. We are focused on converting this LOI into a definitive agreement and, subject to completing that agreement and satisfying all applicable requirements, making Cyprus another meaningful market for Tempramed. This planned expansion further demonstrates the international relevance of our passive, battery-free technology for people who rely on temperature-sensitive medications."

About Tempramed Technologies Ltd.

Tempramed Technologies is a global medical device company with a portfolio of innovative, temperature-controlled medication-storage solutions. Founded with the mission to safeguard the effectiveness of life-saving medications, Tempramed develops patented, FDA-registered (U.S. Food and Drug Administration) thermal insulation devices that operate continuously without batteries or external power. Its commercial product portfolio includes Vivi Cap, Vivi Cap Smart, Vivi Epi and Vivi Med. Tempramed enables patients and health care providers to confidently manage temperature-sensitive medications anywhere, any time.

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