Dr. Amir Inamdar reports

CYBIN APPOINTS DR. ATUL MAHABLESHWARKAR M.D., AS SENIOR VICE PRESIDENT, CLINICAL DEVELOPMENT

Dr. Atul R. Mahableshwarkar, MD, DLFAPA, has joined Cybin Inc. as senior vice-president, clinical development. Dr. Mahableshwarkar will lead the development of the CYB003 program, Cybin's proprietary deuterated psilocybin analog which has received U.S. Food and Drug Administration (FDA) breakthrough therapy designation for the adjunctive treatment of major depressive disorder.

"We are delighted to welcome Dr. Mahableshwarkar to the Cybin team at this critical juncture in the company's progression," said Dr. Amir Inamdar, chief medical officer of Cybin. "As we approach the initiation of our phase 3 study of CYB003, Dr. Mahableshwarkar's deep experience of successfully running global phase 3 programs will be invaluable. His broad expertise across strategic, developmental and regulatory domains will no doubt contribute to accelerating Cybin's path forward," concluded Dr. Inamdar.

"With the imminent commencement of its phase 3 study of CYB003, and the initiation of a phase 2 study of CYB004, the company's proprietary deuterated dimethyltryptamine (DMT) program for the treatment of generalized anxiety disorder (GAD), this is an exciting time for Cybin," stated Dr. Mahableshwarkar. "I am extremely encouraged by the recently published positive data across the company's lead pipeline products and believe that my experience overseeing smaller proof of principal/concept as well as large, complex, global phase 3 trials will contribute to Cybin's success advancing its portfolio of candidates. I share Cybin's commitment to bringing forward improved therapeutics for patients who suffer with mental health disorders and look forward to contributing to the team's efforts," concluded Dr. Mahableshwarkar.

Dr. Mahableshwarkar is a board-certified psychiatrist and experienced drug development executive with experience in both large global and small start-up companies. He brings varied experiences from academia and industry as a site principal investigator for industry-sponsored studies and has submitted several investigational new drug and new drug applications leading to drug approvals. With a focus on drug development strategy and oversight, he has designed and conducted global clinical trials in Alzheimer's disease, anxiety disorders, bipolar disorder, major depression, Parkinson's disease and schizophrenia, and led the development program resulting in the approval of a novel antidepressant.

Dr. Mahableshwarkar graduated from the Armed Forces Medical College in India and completed a residency in psychiatry and a fellowship in neuropsychiatry from the Rosalind Franklin University of Health Sciences/the Chicago Medical School, where he was an associate professor and vice-chair of the department of psychiatry and behavioural sciences. He also led the mental health services product line at the North Chicago VAMC, where he managed the mental health care for veterans. He has more than 180 scientific publications/posters/oral presentations to his credit.

About Cybin Inc.

Cybin is a clinical-stage biopharmaceutical company on a mission to create safe and effective psychedelic-based therapeutics to address the large unmet need for new and innovative treatment options for people who suffer from mental health conditions.

Cybin's goal of revolutionizing mental healthcare is supported by a network of world-class partners and internationally recognized scientists aimed at progressing proprietary drug discovery platforms, innovative drug delivery systems, and novel formulation approaches and treatment regimens. The company is currently developing CYB003, a proprietary deuterated psilocybin analog for the treatment of major depressive disorder, and CYB004, a proprietary deuterated DMT molecule for generalized anxiety disorder, and has a research pipeline of investigational psychedelic-based compounds.

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