Mr. Philip Williams of IsoEnergy reports

ISOENERGY INCREASES STRATEGIC HOLDING IN PREMIER AMERICAN URANIUM INC.

IsoEnergy Ltd. has agreed to acquire 13,642,775 common shares of Premier American Uranium Inc. (PUR) held by Sachem Cove Opportunity Fund LP in consideration for the issuance of an aggregate of 387,491 common shares of the company (the ISO shares). The ISO shares were issued at a deemed price of $11.763 per share, representing aggregate consideration of $4,558,057. Closing of the transaction is subject to the satisfaction of certain customary closing conditions, including the approval of the Toronto Stock Exchange with respect to the issuance of the ISO shares.

The transaction will transfer Sachem Cove's position in Premier American Uranium to IsoEnergy, a founding and strategic shareholder, further strengthening IsoEnergy's exposure to U.S. uranium development and in situ recovery exploration. Premier American Uranium will not issue any securities or receive any proceeds in connection with the transaction. The increased investment follows Premier American Uranium's completion of a $5-million (U.S.) strategic investment by DISA Uranium Corp. in subscription receipts of Premier American Uranium priced at 75 Canadian cents each, representing a 41.5-per-cent premium to Premier American Uranium's closing share price on Sept. 14, 2026, the last trading day before that investment was announced. The subscription receipts will convert into Premier American Uranium common shares upon satisfaction or waiver of the applicable escrow release conditions. IsoEnergy is also a significant shareholder of DISA Uranium (see Premier American Uranium news releases dated Sept. 15, 2026, and Nov. 10, 2026).

Philip Williams, chief executive officer and director of IsoEnergy, commented: "We are pleased to increase our position as a strategic shareholder of PUR as it advances the Cebolleta uranium project in New Mexico and pursues significant discovery potential through ongoing ISR exploration in Wyoming. We believe the recent weakness in PUR's share price does not reflect the value of its development portfolio and exploration upside, creating an attractive opportunity to add to our holdings. This transaction further strengthens our exposure to the U.S. uranium sector, which spans near-term production, development and exploration, through our own portfolio and investments in DISA Uranium and PUR. DISA Uranium's recent investment in PUR further reinforces the strategic support behind PUR as it pursues an exciting next phase of growth."

Immediately prior to the completion of the transaction, the company owned an aggregate of 7,493,601 Premier American Uranium shares and warrants to acquire 3,060,127 Premier American Uranium shares, representing approximately 7.8 per cent of the current outstanding Premier American Uranium shares on a non-diluted basis and approximately 10.7 per cent of the current outstanding Premier American Uranium shares on a partially diluted basis assuming exercise of all of the warrants held by the company.

Assuming completion of the transaction, the company is deemed to own an aggregate of 21,136,376 Premier American Uranium shares and warrants to acquire an aggregate of 3,060,127 Premier American Uranium shares, representing approximately 22.1 per cent of the current outstanding Premier American Uranium shares on a non-diluted basis and approximately 24.5 per cent of the current outstanding Premier American Uranium shares on a partially diluted basis assuming exercise of all of the warrants held by the company.

The securities of Premier American Uranium held by IsoEnergy are held for investment purposes. Although IsoEnergy has no current plans with respect to the securities, depending on market conditions, general economic and industry conditions, trading prices of Premier American Uranium's securities, Premier American Uranium's business, financial condition, and prospects and/or other relevant factors, IsoEnergy may develop such plans or intentions in the future, and, at such time, may from time to time acquire additional securities, dispose of some or all of the existing or additional securities or may continue to hold securities of Premier American Uranium. The Premier American Uranium shares are being acquired by IsoEnergy pursuant to an exemption under Section 4.2 of National Instrument 62-104, Take-Over Bids and Special Transactions.

This news release is issued pursuant to National Instrument 62-103, The Early Warning System and Related Take-Over Bid and Insider Reporting Issues, which also requires an early warning report to be filed with the applicable securities regulators containing additional information with respect to the foregoing matters. A copy of the early warning report of IsoEnergy will be available under Premier American Uranium's profile on SEDAR+. IsoEnergy's registered office is located at 217 Queen St. W, Toronto, Ont., M5V 0R2.

About IsoEnergy Ltd.

IsoEnergy is a leading, globally diversified uranium company with substantial current and historical mineral resources in top uranium mining jurisdictions of Canada, the United States and Australia at varying stages of development, providing near-, medium- and long-term leverage to rising uranium prices. IsoEnergy is currently advancing its Larocque East project in Canada's Athabasca basin, which is home to the Hurricane deposit, boasting the world's highest-grade indicated uranium mineral resource.

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